HFmrEF ICD-10 Code: I50.40

Last updated: January 31, 2025

There is no specific ICD-10 code for HFmrEF (heart failure with mildly reduced ejection fraction). The most appropriate code is I50.40 (Unspecified combined systolic and diastolic heart failure) or I50.89 (Other heart failure) depending on how it's documented.

Understanding HFmrEF

HFmrEF is defined as heart failure with ejection fraction between 41-49%. It sits between:

  • HFrEF (reduced EF): EF ≤ 40% → Systolic heart failure (I50.2x)
  • HFpEF (preserved EF): EF ≥ 50% → Diastolic heart failure (I50.3x)
  • HFmrEF (mildly reduced EF): EF 41-49% → No specific code

Coding Options for HFmrEF

Since ICD-10-CM doesn't have a dedicated HFmrEF code, consider these options:

CodeWhen to Use
I50.40Combined systolic and diastolic HF - often appropriate since HFmrEF shares features of both
I50.42Chronic combined HF - if chronic/stable
I50.89Other heart failure - if "HFmrEF" is specifically documented
I50.9Heart failure, unspecified - last resort

Coding Clinic guidance: When documentation specifies "HFmrEF" or "heart failure with mildly reduced ejection fraction," many facilities use I50.89 (Other heart failure) as it's the most accurate representation of a heart failure type that doesn't fit the standard systolic/diastolic classification.

Code Selection by Acuity

If acuity is documented:

AcuityCombined HF Code
AcuteI50.41
ChronicI50.42
Acute on chronicI50.43
UnspecifiedI50.40

Common Coding Scenarios

Scenario 1: HFmrEF, Chronic, Stable

Documentation: "Chronic HFmrEF, EF 45%, stable on guideline-directed therapy."

Code: I50.42 (Chronic combined systolic and diastolic heart failure) or I50.89 (Other heart failure)

Rationale: Either code is defensible. I50.42 captures the chronic nature and mixed pathophysiology. I50.89 may better reflect the specific HFmrEF terminology.

Scenario 2: Acute Decompensated HFmrEF

Documentation: "Acute decompensated heart failure, known HFmrEF, EF 43%."

Code: I50.41 (Acute combined systolic and diastolic heart failure)

Rationale: The acute decompensation takes precedence. Use the acute combined code since HFmrEF has features of both systolic and diastolic dysfunction.

Scenario 3: New Diagnosis of HFmrEF

Documentation: "New diagnosis heart failure with mildly reduced ejection fraction (EF 47%). Starting lisinopril."

Code: I50.40 or I50.89

Rationale: Without acuity specified, use unspecified combined HF or other HF.

Why No Specific Code?

ICD-10-CM's heart failure classification is based on the older systolic/diastolic terminology:

  • Systolic HF = HFrEF (reduced EF)
  • Diastolic HF = HFpEF (preserved EF)

HFmrEF is a newer clinical category from the 2016 ESC heart failure guidelines. ICD-10-CM updates haven't yet created a specific code for this classification. Until they do, coders must use the best-fit existing codes.

Documentation Recommendations

When coding HFmrEF, look for:

  • Specific EF percentage (to confirm 41-49% range)
  • Acuity: acute, chronic, or acute on chronic
  • Any underlying cause (ischemic, hypertensive, etc.)
  • Whether the provider documents "combined" dysfunction

If documentation just says "heart failure" without EF or type, query for specificity.

Frequently Asked Questions

What is the ICD-10 code for HFmrEF?

There is no specific ICD-10 code for HFmrEF (heart failure with mildly reduced ejection fraction). Most facilities use I50.40 (Combined systolic and diastolic heart failure) or I50.89 (Other heart failure) depending on documentation and facility guidelines.

Why isn't there a specific HFmrEF code?

ICD-10-CM uses the older systolic/diastolic classification rather than the newer EF-based categories (HFrEF, HFmrEF, HFpEF). HFmrEF was defined in 2016 guidelines, and ICD-10-CM hasn't yet been updated with a specific code.

Should I use systolic or diastolic codes for HFmrEF?

HFmrEF typically has features of both systolic and diastolic dysfunction, so combined heart failure codes (I50.4x) are often most appropriate. Avoid using pure systolic (I50.2x) or pure diastolic (I50.3x) codes unless documentation supports that classification.

Related Resources

Last updated: January 2025. Code data reflects ICD-10-CM 2026 version. This guide is for educational purposes only. Always verify codes against current official guidelines.