Pancytopenia ICD-10 Code: D61.818
Last updated: January 4, 2026
Pancytopenia (low RBC, WBC, and platelets) is primarily coded as D61.818 (Other pancytopenia).
Pancytopenia Code Selection
| Code | Description | Use When |
|---|---|---|
| D61.818 | Other pancytopenia | Most pancytopenia cases |
| D61.810 | Antineoplastic chemotherapy induced pancytopenia | Post-chemo |
| D61.811 | Other drug-induced pancytopenia | Non-chemo drug cause |
| D61.89 | Other specified aplastic anemias | If aplastic anemia documented |
| D61.9 | Aplastic anemia, unspecified | NOS aplastic anemia |
Etiology Coding
Always code the underlying cause when known:
| Cause | Primary Code | Pancytopenia Code |
|---|---|---|
| MDS | D46.x | + D61.818 |
| Leukemia | C91-C95 | + D61.818 |
| Chemotherapy | T45.1X5- | + D61.810 |
| Other drugs | T-code | + D61.811 |
| Aplastic anemia | D61.0-D61.3 | (inherent) |
| B12 deficiency | D51.x | + D61.818 |
Coding Tips
- Code etiology first: MDS, leukemia, drug toxicity
- Chemotherapy: Use D61.810 specifically for chemo-induced
- Query if cause unknown: Unexplained pancytopenia needs workup
- Sequencing: Underlying condition before pancytopenia
Related Codes
Frequently Asked Questions
D61.818 (Other pancytopenia) is the primary code. Use D61.810 for chemotherapy-induced or D61.811 for other drug-induced pancytopenia.
Use D61.810 (Antineoplastic chemotherapy induced pancytopenia). Also code the malignancy and T45.1X5- for the adverse effect of antineoplastic drugs.
Yes. Code the MDS (D46.x) as primary, then add D61.818 for the pancytopenia manifestation. The pancytopenia provides clinical specificity.
Related Resources
Last updated: January 2026. Code data reflects ICD-10-CM 2026 version. This guide is for educational purposes only. Always verify codes against current official guidelines.